基于穿支动脉-神经组织单元论分水岭脑梗死分型及脑白质疏松的形成

Abstract

At present, there is still controversy in the etiology and pathogenesis of cerebral watershed infarction (CWI). The classification of watershed infarction is also confusing. Great changes have taken place in the knowledge of CWI with the development of the medical and imaging technology. Based on the concept of the perforating artery-neural tissue units, the innovative speculation on the relation among leukoaraiosis (LA) (belong to white matter lesions), CWI and the mechanism of the perforating artery infarction formation was proposed in this paper. Based on the combination possibility of different perforating artery-neural tissue units, the CWI was classified as lateral watershed infarction (anterior cortical and posterior cortical watershed infarction), internal watershed infarction (anterior and interior type, posterior and interior type and interior type) and deep watershed infarction (deep anterior type, deep posterior type and the various subtypes). This paper suggests that LA might be caused by chronic watershed cerebral ischemia change, and perforating artery infarction and CWI are the same strain. This inference may help us to understand the relation among the mechanisms of the perforating artery infarction, CWI and LA.