Abstract
A drug which reduces the need of surgery is required in the treatment of otitis media with effusion (OME) in children. We investigated the clinical efficacy of s-carboxymethylcysteine (S-CMC) without surgery on OME in children. S-CMC in a dose of 30mg/kg/day was administered for 2 weeks to 44 children (61 ears) under ten years of age with OME. The efficacy was evaluated at the end of treatment.1) In the 61 ears treated, responses were excellent in 3 (4.9%), good in 14 (23.0%), moderately good in 13 (21.3%), fair in 28 (45.9%), and poor in 3 (4.9%).2) An adverse reaction was noted in only one of the 44 patients (2.3%).
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