Abstract

Aim. To study the state of central hemodynamics measured with echocardiography in patients with chronic renal disease on the background of chronic pyelonephritis caused by nephrolithiasis and dysmetabolic nephropathy in the phase of incomplete remission and combined with arterial hypertension. Materials and methods. 81 patients with chronic renal disease on the background of chronic pyelonephritis associated with nephrolithiasis in the phase of incomplete clinical and laboratory remission were investigated. Age varied from 25 to 60 years, average age was 46 ± 9.0 years. The study wasperformed at “Tyumen RZHD – hospital” and “Tyumen SMU – multidisciplinary clinic”. Results. Patients with chronic renal disease on the background of chronic pyelonephritis and arterial hypertension had impaired left ventricular diastolic function, characterized by a significant increase in such indicators as the rate of early and late LV filling and the time of isovolumetric relaxation, a decrease in the E/A ratio, with preserved systolic function of left ventricular. Conclusion. Patients with chronic renal disease on the background of chronic pyelonephritis due to nephrolithiasis, combined with arterial hypertension in the absence of severe left ventricular hypertrophy, have diastolic function disorders, preserved left ventricular systolic function, which may contribute to the chronic heart failure.

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