Abstract
A series of experiments was performed on the effect of some antibiotics (penicillin G, dihydrostreptomycin, streptomycin calcium chloride complex, chloromycetin, aureomycin and pyrimidin-penicillin) on the blood-sugar level in the normal, hyper- or hypoglycemic rabbit by Hagedorn-Jensen's method. Result : (1) No effect was observed by penicillin and chloromycetin on the blood-sugar level, and little effect by dihydrostreptomycin and pyrimidin-penicillin. (2) Streptomycin calcium chloride complex exerted a slight rise in this level. It seemed probably to be ascribed to the histamine-like action involved when administered.streptomycin. (3) Aureomycin decreased slightly the blood-sugar level. This hypoglycemia turned over to normal by vitamin B complex, especially by vitamin B2 as well as niacin. Briefly to say these antibiotics studied here have no significant effects on the blood-sugar level of rabbits.
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