ВЛИЯНИЕ СОЛЕЙ СВИНЦА НА БИОХИМИЧЕСКИЕ ПОКАЗАТЕЛИ В ЛИМФЕ ЖИВОТНЫХ

Abstract

The article establishes the effect on the biochemical parameters of animal lymphocytes in case of poisoning with lead salts. The impact of lead salts, their spread, the effect of the harmful factors and the strengthening of the ecological situation in the environment determine the urgency of this problem. It is known that heavy metal ions gradually accumulate in the elements of the environment and then pass from the atmosphere to water and the human body. It was found that the effect of heavy metal salts in rats, including lead salts, has a negative effect on the lymphatic and circulatory system compared to the control group of biochemical parameters, which leads to metabolic disorders in the blood and lymph circulation. As a result of the study, the activity of rat enzymes was detected in normal and after poisoning with a toxicant. In acute poisoning, there was an increase in the amount of alkaline phosphatase in the lymphatic system by 40%, as well as an increase in the level of amino-transferase enzymes by 71% and 83%, respectively, and a decrease in the content of total bilirubin and associated bilirubin, all this indicates a violation of liver function, increased cytological processes in the liver and pancreas, decreased protein synthesis and impaired metabolism. When exposed to lead salts on the biochemical parameters of the lymph, the activity of α-amylase was reduced by 22.7%. based on the experiments, it was found that heavy metal salts significantly reduce the level of glucose in the blood, which negatively affects the parenchyma of the liver, kidney and kidney, increasing its consumption in tissues. The results obtained in the course of the study allowed us to form comprehensive data on the effect of lead on lymphatic and circulatory activity, biochemical parameters of the lymph of animal rats and can serve as a scientific basis for finding solutions to this problem.