Abstract

Odontogenic ghost cell tumor, considered to be a solid type of calcifying odontogenic cyst, is a rare entity, and only a few cases have been reported in the English and Japanese literature. Here, we report a case of odontogenic ghost cell tumor in a 59-year-old man. The patient presented with a painless swelling in the mandible. The swelling extended from the first right molar region to the ramus. Radiography revealed a relatively well defined radiolucent lesion containing some irregularly-shaped radiopaque masses and an impacted third molar. Segmental resection and reconstruction with an iliac cancellous bone graft and a titanium mesh plate were performed. Histopathologically, there was evidence of tumor invasion of the periphelial cortical bone, areas consisting of large amounts of calcifying flaky keratin close to masses of ghost cells, and dysplastic dentinoid matrix adjacent to epithelial cell nests. Atypical mitosis was not found. A final diagnosis of “central odontogenic ghost cell tumor” was made. Three years after operation, the patient is well with no signs of recurrence.

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