Abstract
Vertebrate bone, tooth dentin and enamel, are composed of the so-called biological apatite, though these hard tissues originate and grow in a different manner and show their characteristic microscopic and ultramicroscopic textures. Tooth enamel has the largest and most perfect apatite crystals among them, even though the enamel crystals contain many crystal-imperfections. To realize the formation of these biological apatite, cell mediated crystal formation mechanisms are shortly reviewed.
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