Abstract
The present study describes the results of chemotherapy by cisplatin combined with the radiation therapy. A total of 12 patients with the head and neck cancer were treated. The location of the primary site was the maxillary sinus in 4 cases, the tongue in 2 cases, the maxillary gingiva in 2 cases and the mandibular gingiva in 2 cases. The buccal mucosa and mandibular bone were affected in each one case. The Histological types of the tumors were squamous cell carcinomas in 11 cases and adenocarcinoma in one case.Six patients were treated by intraarterial injection of cisplatin and another six patients were treated by intravenous injection of cisplatin. Total dose from 30 to 50 Gy of irradiation was administrated to both groups. Results of the therapy of 10 patients were CR in 6 cases, PR in 3 cases and NC in one case. The CR rate was 60 percent and PR rate was 30 percent. CR was achieved in all 4 cases treated by intraarterial administration of cisplatin.
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