Abstract
A 51-year-old Japanese male who had spent six months in Saudi Arabia was diagnosed by biopsy in his right thigh as having cutaneous leishmaniasis and was successfully treated with metronidazole and local heat. The dose of metronidazole used was 250 mg three times a day, and the drug was given for three ten-day periods with intervening rest periods of ten days. Leishmania promastigotes could be cultured from the lesion on the first day that metronidazole was administered but could not be cultured after two ten-day periods of treatment with the drug. After medication was given, local heat therapy was applied at 42°C, using hot water in a vinyl bag, for a total of 29 hrs, and heating under an infrared lamp at 43°C for 1 hr on one occasion only. Details of heat treatment are given in Table 1.
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