Abstract
Epithelial-myoepithelial carcinoma (EMC) comprises approximately 1% of all salivary gland tumors. EMC generally occurs in the parotid gland; EMC arising in the minor salivary gland is extremely rare.We present a rare case of EMC arising in the minor salivary gland. A 54-year-old woman visited our hospital because of swelling of the left side of the soft palate.The clinical diagnosis was a salivary gland tumor. The tumor was resected under local anesthesia on June 18, 1994. Pathologically, the tumor was composed of two-layer duct-like structures formed by an outer layer of clear cells and an inner layer of epithelial cells, as well as by solid clear cells and spindle-shaped cells. Immunohistochemically, these clear cells showed positive reactivity for S-100 protein, HHF35 (actin), glial fibrillary acidic protein (GFAP), and vimentin. The inner epithelial cells reacted with polyclonal keratin, epithelial membrane antigen (EMA), amylase, and secretory component (SC). The results indicate that the tumor had on epithelial-myoepithelial origin as reported previously by others. The patient had a good prognosis, and there has been no evidence of local reccurrence or distant metastasis as of 3 years after operation.
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