한의학 고전 문헌과 현대 약리 연구에서 보고된 백출(白朮)의 효능에 관한 비교연구

Abstract

It was studied to compare between efficacies of Atractylodes Rhizome recorded in Traditional Korean Medicine literatures and pharmacological efficacies identified in recent studies. Traditional uses of Atractylodes Rhizome were collected from thirteen herbal books and five medical books, and pharmacological efficacy studies were collected from three digital databases. After the WHO-ATC classification criteria was used to sort types of the efficacies, comparison between traditional uses and pharmacologically identified efficacy was performed. Two hundred thirty-five efficacies collected from traditional literatures were classified into twenty-six efficacy types. Sixty-five pharmacological efficacy studies collected from three databases reported forty efficacy types. Traditional literatures and experimental studies were most commonly reported gastrointestinal system-related efficacies. It was found that most pharmacological efficacy studies examined main efficacies which had already recorded in traditional literatures. There were studies which examined the efficacy for gastrointestinal disorders, musculoskeletal anti-inflammation, diuretic effect, the inhibitory effect of uterine contraction and the whitening effect (nine, six, three, one, and one, respectively). On the other hand, opposite efficacy and new potential efficacies were also observed. There were two studies reported the effect for constipation, but most traditional literatures recorded antidiarrheal effect. In addition, there were studies which found hypoglycemic antidiabetic, antineoplastic, and antioxidative effect (five, eight, and three, respectively). Most experimental studies were inspired by traditional uses recorded traditional medical literatures. Some studies found efficacies contrary to traditional uses or new potential efficacies.