多次元ガスクロマトグラフ‐飛行時間型質量分析計による水酸化ＰＣＢの測定に関する検討

Abstract

We developed for accurate measuring method of mono-hydroxyl polychlorinated biphenyls (HO-PCBs) which has 839 of ideal congeners by coupling comprehensive gas-chromatograph (GC×GC) and high resolution time-of flight mass spectrometer (HRTOFMS). One hundred and nineteen of HO-PCB standard isomers were measured to determine the retention time on the two-dimensional chromatograms of GC×GC-HRTOFMS and then the method was applied to river sediment samples.Under optimized condition of the GC×GC-HRTOFMS equipped a 5%-phenyl/methyl silicorn (as 1st column) and a 50%-phenyl/methyl silicorn capillary column (as 1st column), 111 peaks were obtained on the two-dimensional chromatogram. Only 5% of peak separation was improved against generic a GC.One hundred and fifty two peaks derived from HO-PCBs in river sediment were detected by the GC×GC-HRTOFMS although 125 peaks detected by single GC mode. Methyl derivatized HO-PCB was, however, not identified in major peaks on the chromatograms of the GC×GC-HRTOFMS because of inefficient sensitivity of the detector and foreign substances.To more utilize this method, it is necessary to improve sensitivity and dynamic range of detector on a TOFMS and develop a new software allows easy quantification and identification on data of a GC×GC-HRTOFMS.