Abstract
Four cases of intraosseous squamous cell carcinoma (IOSCC) of the maxilla were identified among the 303 patients with malignant tumors who visited our clinic since February 1979. IOSCC was defined by the following criteria: 1) The tumor tissue is histologically assessed to be squamous cell carcinoma. 2) No ulcer derived from the tumor tissue is observed in the oral, nasal, or sinus mucous membranes. 3) Three-dimensional CT or MRI examination indicates that the tumor exists in the maxillary bone. 4) It is histologically confirmed that the basal layer of the covering epithelium is intact and that the main site of the tumor tissue is in the bone. IOSCC tended to metastasize to the cervical lymph nodes in contrast to squamous cell carcinomas of the maxillary sinus.
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