Abstract
Background. Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. There is paucity of information regarding gender differences in outcomes of patients undergoing AF catheter ablation. The aim of this prospective study was to determine gender differences in clinical characteristics, quality of life (QoL) and outcomes of the patients referred for AF catheter ablation. Methods. The study comprised of 55 patients (25 men) with symptomatic AF, who were referred for pulmonary vein isolation. A variety of clinical characteristics, echocardiography parameters, QoL before and after catheter ablation, safety and efficacy of the procedure over 12-months follow-up period were compared between men and women. Results. At the baseline, women had lower values of psychological parameters of QoL comparing to men (15,9 vs 19,9, p < 0.05), and more severe symptoms. Within 12 months after the procedure arrhythmia recurred in 28 % men and in 40 % women. Women had more complications during the procedure and in early postablation period (12 % women and 5 % men, p < 0.05). All patients with no arrhythmia recurrence had a significant improvement in all QoL domains and a decrease in AF EHRA score. Conclusions. The psychological status of women with AF associated with high degree of clinical manifestations. QOL can be an indicator of the efficacy of catheter ablation.
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