不需標定、即時的液態 放電紡絲纖維一氧化氮感測器

Abstract

Nitric oxide (NO) is a free radical playing important roles in the human body. NO relaxes the smooth muscle in the walls of the arterioles, regulates the blood pressure, and inhibits the aggregation of platelets.1–4 It also serves as a signaling molecule in the nervous system.5 Direct and real-time detection of NO outside the cell helps to unveil how NO relates to certain physiological function. Since the beginning of 20 century, electrospinning had been developed Electrospinning is a process, which produces superfine fibers. Electrospinning is able to produce continuous fibres from the submicron diameter down to the nanometre diameter. A sensing fibrous membrane prepared by electrospinning is demonstrated for real-time and indicator-free detection of nitric oxide (NO) in aqueous solution. The fibers with diameters of 550 nm are composed of NO probe 11,16-Bisphenyl-6,6,21,21-tetramethyl-m-benzi-6,21-porphodimetheno-chloro-Zinc(II) and host polymer polyacrylonitrile. The high surface area of the sensing fibrous membrane gives rapid response in 6 seconds and high sensitivity, and NO concentration detection limit is estimated to be 10−9 M. The sensing fibrous membrane also shows good reversibility, selectivity, and stability in various pH values.