豚副腎皮質の核糖原,細胞質糖原と細胞脂肪との関係

Abstract

Mechanism of adipositas and effect of fattening have been investigated histochemically in various organs of Yorkshire pigs used for Pig Feeding Standard revising test in case of pork production. During these investigations, occurrence of glycogen was found in nuclei and cytoplasms of zona reticularis in adrenals of the pigs. No one ever found glycogen there.Present study describes frequency of occurrence of glycogen-bearing nuclei and cytoplasms, their size and shape and relationship between glycogen-laden cells and fat-stored cells. The results obtained are summarized as follows:1. All of eleven sows and nine hogs investigated contained glycogen-laden nuclei of cells in zona reticularis. In the animals containing remarkably large amount of glycogen-laden nuclei, the similar nuclei were also found in zona fasciculata in 18% of the sows and 22% of the hogs and none in zona glomerulosa.2. Appearance of intranuclear glycogen seemed no to be related to feeding but to be related clearly to sex. The glycogen tended to appear more intensively in hogs than in sows.3. Modus of the intranuclear glycogen deposition were various: i) glycogen occupied all of large or small nuclei, ii) glycogen attached to nuclear membrane and internal space was empty (ringform), iii) round internal bodies located in vacuolized nuclei, iv) flask-like, dumb bell-like or funnel-like bodies attached to one part of nuclear membrane within vacuolized giant nuclei (one kind of internal bodies), v) several granules or rods contained glycogen near chromatin dispered within nuclei (multiple granular form) and vi) hyperchromic or hypochromic glycogen-laden nuclei by stainability to PAS-stain.The vacuolized nuclei with free glycogen were divided into giant nuclei and small nuclei.4. Modus of intracytoplasmic glycogen were divided into three types as follows: i) a large amount of glycogen in entire cytoplasms (entire glycogenic form), ii) glycogen deposition formed round solitary islet near nuclear membrane (glycogenic bodies) and iii) a small quantity of glycogen in cytoplasms (diffuse form).5. On an average, in the section of one zona reticularis, they were indicated as following table: Occurrence of the cells laden the nuclear and cytoplasmic glycogen and cellular fat in the swine adrenalsIn short, it is important that a fact was observed, 1) intranuclear glycogen was related to cytoplasmic glycogen and 2) cellular glycogen in both nuclei and cytoplasms were related to the appearance of fat-stored cells.