Abstract
Toray Industries have manufactured two types of high performance hollow fiber type membranes for artificial kidney. One is PMMA membrane (BK, BG series) and another is polysulfone membrane (BS series). In recent years, many dialysis patients' life came to be saved by progress of dialysis technologies. The number of long-term dialysis patients has increased and the frequent chronic complications of long-term dialysis patients have increased. β2-microglobulin was identified as a major constituent protein of amyloidosis which is one of the complications. PMMA membrane (BK, BG series) and polysulfone membrane (BS series) are designed to remove β2-microglobulin. PMMA membrane (BK, BG series) can remove β2- microglobulin by a high β2-microglobulin adsorption property. Polysulfone membrane (BS series) can remove β2-microglobulin by a high /β2-microglobulin penetration property. We design the form of artificial kidney suitable to the characteristics of PMMA membrane and polysulfone membrane.
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