Abstract
Porous materials show low Young’s moduli and excellent bonding to living bone. However, the strength of such materials is often insufficient in the initial stage of implantation. Thus, the objective of this study was to increase strength and Young’s modulus of porous titanium by filling the pores with a biodegradable mixture of polyglycolide (PGA) and calcium carbonate (CaCO3). The mixture was introduced into porous Ti (porosity: 60%) using a heat injection technique. When the pores were filled with PGA-CaCO3, compressive strength and Young’s moduli were drastically increased and influenced by the content of CaCO3. In an animal test, unfavourable autopsy findings could not be confirmed in rats and no bone was observed in the pores of the Ti-PGA composite. Decomposition of PGA lowered the surrounding pH, it was found to inhibit bone formation in the pores. Addition of CaCO3 to PGA could suppress the decrease in pH.
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