Abstract
Micro-flow synthesis has advantages over conventional batch synthesis such as precise control of the reaction time (<1 sec) and temperature by rapid mixing and high heat and mass transfer. In addition, light-penetration efficiency can be improved in photo-reactions due to the thinness of micro-flow reactors. Moreover, scale-up can be readily achieved with high reproducibility either by continuous running or by numbering up of micro-flow reactors. Increasing number of highly efficient reactions and syntheses have been reported based on micro-flow technology in recent years. We have also developed efficient micro-flow photo-reaction, imidoylation, and acylation by taking the advantages of micro-flow technology. Herein, we wish to report our synthesis of bioactive vitamin D3, its analogues and α-aryl carbonyl compounds based on the micro-flow photo-reaction as well as the synthesis of diimine ligands for olefin polymerization catalysts and peptides based on the micro-flow imidoylation and acylation.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
