Abstract
The insudation of blood plasma components into the intima is one of the most important atherogenic factors. But, the accumulation of blood components would not occur when the intimal fluid transportation (“clearance”) is satisfactory enough to carry them away.We examine microscopically the declining of intimal clearance with aging about non-sclerotic areas of human aortic wall by Berlin-blue production after infusion of ferric citrate solution.The infusion of fluid was much easier and more uniform in the younger aortas than in older cases, and it was washed away by perfusing of saline solution. But in older cases, blue dye remained distinctly in the intima.It was noted that the clearance mechanism of human aortic wall declined steadily with aging even in the non-sclerotic “normal” areas.
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