Abstract
Myoepithelioma is a rare salivary gland neoplasm. Histologically, the tumor is composed of spindle-shaped and/or plasmacytoid cells.Plasmacytoid myoepithelioma of the soft palate was reported in a 53-year-old man. The tumor, measuring 35×25×5 mm, was located on the left side of the soft palate and was surgically removed. Two years later, the patient has not experienced recurrence.Microscopically, the tumor consisted of plasmacytoid cells with round eccentric nuclei surrounded by an abundant homogenous eosinophilic cytoplasm in myxoid stroma.Immunohistochemical studies revealed positive reactions for S-100 protein and vimentin in tumor cells. Electron microscopy demonstrated abundant intermediated filaments filled with tumor cells.A review of the literature indicated that plasmacytoid myoepitheliornas appearred to have a predilection for the oral cavity in younger individuals, while the spindle-cell form tends to occur in the parotid gland in older patients.
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