암 관련 피로(CRF: Cancer-related Fatigue)에 미치는 운동의 효과

Abstract

It has been well known that the cancer-related fatigue(CRF) is one of the most common and distressing side-effects of cancer or/and cancer treatment. In this study, the author reviewed the epidemical, experimental or pilot studies on the prevalence of CRF, the etiology of CRF as well as the effects of exercise intervention for cancer patients with CRF. This study also tried to find any updated exercise guideline of exercise prescription for cancer patients and cancer survivors. To date, it seems that increased pro-inflammatory cytokine activity might be the most potential underlying mechanism of CRF. However, to elucidate the correct etiology of CRF, further controlled and well designed researches are required. Through the review about the effects of exercise intervention for CRF, the author also suggest strongly that exercise should be considered as the most effective approach to deal with CRF and other side effects as well as to improve the patient`s physical function and the quality of life. There are also very important task of developing the relevant and effective exercise program for cancer patients through the cooperation among the oncologists, exercise physiologists, fitness specialists.