Полиморфизм ДНК собак (Canis familiaris L.). V. Однонуклеотидные замены

Abstract

The features of the nuclear genome of dogs, including a number of reference ones, are briefly considered, paying the greatest attention to single-nucleotide DNA polymorphism in the form of so-called SNPs. It is noted that the detection of SNPs implies two processes in the form of their de novo detection by DNA sequencing, including whole genome sequencing, as well as the detection of already known SNPs in genomes during replicative studies on the large experimental material. Some attention is paid to specialized databases and web-resources on canine SNPs. The issues of DNA registration of individual dogs on the basis of single-nucleotide polymorphism are touched upon, which can have various applications, including forensic purposes and for dog control, contributing to the elimination of stray dogs as a class.