Abstract
The purpose of this study is to examine the effects of acute exhaustive exercise on serum BDNF, IGF-1 levels and cognitive function. As study subjects, 16 healthy male college students were selected, and each 8 male college students were assigned to exercise group and control group randomly. In this study, exercise group was carried out treadmill running until all-out and exercise time to exhaustion was recorded. Blood samples were collected two times at pre-test and post-test for the analyses of serum brain-derived neurotrophic factor(BDNF) and insulin-like growth factor-1(IGF-1). Also, Stroop color-word test performed at same times as blood sampling. The results of the study showed that the concentrations of serum BDNF, IGF-1, and Stroop color-word test scores were significantly increased after acute exhaustive exercise(p.05). BDNF and Stroop color-word test scores were significantly higher at post-test in exercise group compared to in control group(p.05). It was also found that there are significant correlations between the changes of serum BDNF and IGF-1(p.05). These results suggest that acute exhaustive exercise has positive effects on cognitive functions by increasing the BDNF.
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