Сравнительная характеристика капилляров 5 слоя моторной коры человека и крысы при ишемии мозга

Abstract

Aim – to reveal existence pf similarities and differences in reaction of capillaries of the 5th layer motor bark at experimental ischemia of at white brain rats and the relevant department of a brain of the person at chronic insufficiency blood supplies because of atherosclerotic damage of brain arteries. Material and methods: on 36 medicines of a brain of white rats at which the model of ischemia of body by bandaging of the left general sleepy was created arteries and 36 – from corpses of 55-90 years suffering from atherosclerotic damage of the arteries feeding a brain with reduction of diameter by 75-85% are studied by histologic techniques a condition of the capillary course of the 5th layer of bark of a motor zone of hemispheres. Results of a research and discussion: similar and not comparable distinction of changes of the microcirculation course of the fifth layer of bark of a motor zone are revealed and rats and the person in the conditions of brain ischemia. It is established that the capillary course at white rats, unlike the person, is steadier against ischemia. Conclusion. Results of the conducted research confirm a hypothesis of the progressing defeat of the microcirculation course of motor bark on to measure of reduction of diameter of brain arteries at the person, demand a certain care at extrapolation of results experiments to clinic.