Abstract

In the treatment of cleft lip and palate, factors such as the timing, method and sequence of lip and palatal closure, as well as the surgeon's skill are thought to markedly influence future maxillofacial development and speech function. Various treatments have been proposed, and many studies have been conducted to assess their usefulness, but no general consensus has been reached. Moreover, scientific studies have not necessarily been conducted to assess outcomes of all treatments.The present article deals with the outline of the six-center comparative study of treatment outcomes in Japanese patients with complete unilateral cleft lip and palate (Japancleft Project 2002-2005) and describes the need for, and benefits of collaborative, inter-center outcomes research to establish efficient and effective management for cleft lip and palate based on scientific findings.

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