Abstract
Twenty-six adult cases of acute exacerbation of chronic otitis media (COM) and twenty cases of acute exacerbation of chronic sinusitis (CS) were treated by Levofloxacin (LVFX) 400mg a day in two divided portions. The clinical efficacy rates were 84.6% for COM and 85% for CS. Bacteriolgical therapeutic failures in treatment were observed in four COM and three CS patients. Adverse response and abnormal laboratory findings were not observed. LVFX was more effective when given at 400mg a day in two divided portions.
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