Abstract
A Clear Cell Sarcoma (C. C. S.) producing melanin pigments similar to malignant melanoma (M. M.) was first described by Enzinger in 1965, even though C. C. S. is deeply located, arising from structures such as tendons. We report on a 21 year-old male referred to us with a right swollen heel revealing radiographic osteolytic destruction in the calcaneus. Histologically the tumor was characterized by pale-staining tumor cells arranged in nests. Hemosideroid granules were identified as melanin by Fontana-Masson staining and positive HMB-45. Vimentin, S-100 and N. S. E. were positive, while keratin, E. M. A. were negative. A syme amputation was performed, preserving the anterior planter flap to cover the heel followed by a 5cm lengthening of the tibia. Metastases to the popliteal lymph node was found two months post operatively, and the patient died with diffuse lymph node and lung metastases. Prognosis of this C. C. S. case was poor even after chemo-immuno therapy.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
