Клинические аспекты ларингофарингеального рефлюкса

Abstract

Laryngopharyngeal reflux (LPR) as the cause of symptoms in the absence of symptomatic gastroesophageal reflux disease (GERD) is often questioned. But it is worth remembering that GERD is a whole complex of symptoms that occur when the mucous membrane is damaged. We aimed to study the clinical symptoms of LPR without esophageal symptoms. The study included 66 women and 34 men with complaints typical of LPR, aged 18 to 70. The study included patients with typical LPR complaints without esophageal symptoms who rated them at more than 13 points according to the RSI questionnaire. 91 patients (95%) complained of hoarseness; 93 (97%), of a sore throat; 88 (92%), of excessive mucus coughing up or its running off from the nose; 36 (38%), of difficulty swallowing; 43 (45%), of coughing after eating or after lying down; 68 (71%), of shortness of breath or episodes of suffocation; 64 (67%), of excruciating or hacking cough; 84 (88%), of feeling of something sticky in the throat or a lump in the throat. In addition to the typical symptoms of LPR, patients may experience difficulty in nasal breathing; sneezing in the absence of respiratory allergies; burning and bitterness in the mouth; bad breath due to the formation of tonsilloliths; complaints from the ear not recorded by objective methods of research. 23% of patients with LPR suffer from carcinophobia. We concluded that LPR affects the larynx and all parts of the pharynx. The appointment of omeprazole 20 mg 30 minutes before meals in the morning 1 time per day for 6 weeks significantly reduces the symptoms of LPR. A new questionnaire is required for the early detection of LPR symptoms by a questionnaire method.