Abstract

We describe an unusual case of polymorphous low-grade adenocarcinoma arising from the inner side of the upper lip of a 48-year-old woman. This tumor was firstly reported by Evans and Batsakis (1984) and was adopted as a new entity in the subclassification of adenocarcinoma by the World Health Organization Classification (1991). The clinical course and histopathological and immunohistochemical characteristics are described with a literature review concerning this case. Histologic features include a variety of growth patterns, such as ductal, trabecular, and solid structures. Immunohistochemical analyses showed positive stainings for cytokeratin, vimentin, and S-100 protein. In addition, a few cells forming ductal structures also stained positively for epithelial membrane antigen.

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