Abstract
We report here a case of Hydrops foetails found in a pregnant woman with low titer anti-Jra antibody. The antibody titer was 1:8, and the immunoglobulin subclass was IgG1 and IgG4. The newborn had the same antibody as mother's in its serum, and its red cells were positive for direct anti-globulin test. The elution of antibody bound to baby's red cells was also confirmed by polyethylene glycol (PEG)-indirect anti-globulin test.The direct evidence, in which Hydrops foetalis was originated from immunological reaction between low-titer anti-Jra antibody and Jra-positive red cells, was not obtained. However, it was presumed that an altered circulatory condition by congenital left heart hypoplasia of the foetus accerelated its hemolytic reaction.
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