Abstract
Autoimmune hepatitis (AIH) has all the characteristic signs of an autoimmune disease, has a variability of clinical manifestations, depending on age, gender, the presence of concomitant pathology, hormonal background, may differ in the frequency of immune-mediated diseases, serological profile, unequal response to immunosuppressive therapy (IST), have different variants of the onset, course and outcome of the disease. All this complicates the diagnosis and determines the expediency of isolating clinical AIH phenotypes. The recognition of AIH phenotypes in various clinical situations is crucial, since early diagnosis and timely IST can not only improve the quality of life, preserve the ability to work, but in some cases save the patient's life. In this article, we conduct a comprehensive review of the clinical phenotypes of AIH, emphasizing the clinical heterogeneity of the disease.
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