Профілактика грибкової інфекції стоп

Abstract

The objective of the work: to study the antifungal activity in vitro and to determine the effectiveness of using the spray containing 0.2% climbazole for the prevention of fungal infections of the feet. Materials and methods. 47 patients were under observation who received treatment at the clinic of the State Establishment «Institute of Dermatology and Venereology of NAMS of Ukraine» for mycosis of the feet and were discharged in a state of recovery, confirmed by mycological negativity. When discharged, patients with a preventive purpose were recommended to apply a spray containing 0.2% climbazole (Mycosan spray) to dry and clean skin twice a day for 30 days with a five-day break for two months. Control of microscopic examination for fungi was carried out once every 2 weeks for two months. To study the protective antifungal activity of the spray in vitro studies were carried out with cultures of yeast-like fungi (Candida spp., strain No. 491) and dermatophytes (Trichophyton rubrum, strain No. 181). Results. The article reveals the relevance of the topic, describes the probable causes of relapses and reinfections of a fungal infection of the feet, indicates ways to prevent these causes. The emphasis is placed on the fact that the main goal of therapeutic and prophylactic measures for fungal infection is the early detection and adequate treatment of patients with mycoses and onychomycosis, as well as the development of fundamentally new means of prevention, one of which is the spray containing 0.2% of climbazole, related to group of azoles which has a fungistatic effect, has a low level of resistance, provides protection and care for the skin of the feet. Conclusions. Studies have shown that Mycosan spray inhibits the growth of pathogenic dermatophytes and yeast-like fungi in vitro. During the observation of 47 patients in the stage of clinical and mycological recovery for two months, infection of the fungal infection of the feet was not observed in a single patient. The spray containing 0.2% of climbazole can be used as an individual prevention of infection and reinfection, as well as an effective addition to the complex therapy of patients with mycoses and onychomycosis of the feet.