Abstract

Acute tonsillopharyngitis (ATP) is one of the most common diseases that makes patients to search for primary medical care. In clinical practice, the differential diagnosis of streptococcal and viral pharyngitis is based on clinical manifestations along with express diagnostics. In pharyngitis caused by group A b-hemolytic streptococcus, febrile temperature, sore throat, plaque on the tonsils and lymphadenopathy in the anterior part of the neck are most characteristic signs and symptoms, while viral pharyngitis is typically associated with conjunctivitis, rhinitis, cough and diarrhea. In streptococcal pharyngitis, antibacterial therapy is in-dicated to prevent potential severe complications (including acute rheumatic fever and glomerulonephritis) while in viral pharyngitis – symptomatic treatment and plenty of drinking. In addition, ATP may be a symptom of infectious mononucleosis, acute retroviral syndrome in primary HIV infection and Kawasaki disease, pharyngeal diphtheria and hematological diseases. Purulent infections, including Lemierre's syndrome, Ludwig's angina, paratonsillitis, parapharyngitis, and retropharyngeal abscess, should also be considered in the differential diagnosis of ATP.

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