Abstract
Some cases with abnormal laboratory data which is not related to the disease have been reported. The reason which appears the abnormal laboratory data are : ① interaction between immunoglobulins and other serum proteins, ② reaction with assay reagents, ③ nonspecific reaction by heterophil antibody, ④ association with antibody activity, ⑤ difference of reactivity between antisera and subclass of immunoglobulins. About this abnormal reaction, the immunochemical characterization, clinical significance, and laboratory detection of abnormal data are introduced.
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