Abstract
Withania somnifera (L.) Dunal, also known as ashwagandha or Indian ginseng, is widely used in traditional oriental medicine. Modern research confirms the applicability of withanolides and other compounds from withania roots in treatment of various diseases. However, the massive gathering of W. somnifera for the purposes of traditional medicine puts the species at risk of extinction. Since this plant is sensitive to climatic conditions, production of W. somnifera hairy root cultures in bioreactors is the most promising cultivation method. This method allows to produce biomaterial of high purity, with a stable content of biologically active substances. A large amount of data has been obtained on the optimal conditions for accumulation of biomass, increasing the content of withanolides and their extraction from the roots of W. somnifera. The review of data suggests good prospects for the production of pharmaceuticals to treat a wide range of diseases.
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