ВОЗРАСТ-АССОЦИИРОВАННЫЕ ПРОБЛЕМЫ ПРИ SARS-COV-2-ИНФЕКЦИИ У КОМОРБИДНЫХ БОЛЬНЫХ, ПРОЖИВАЮЩИХ НА ТЕРРИТОРИИ, ПРИРАВНЕННОЙ К КРАЙНЕМУ СЕВЕРУ. КЛИНИКО-ЭПИДЕМИОЛОГИЧЕСКИЙ АНАЛИЗ

Abstract

Abstract. The study aims to analyze the course of SARS-CoV-2 infection and age-associated therapeutic comor-bidities in groups of elderly patients in order to detect their interrelation and determine the diagnosis. Based on the data obtained from domestic and foreign literature on redictors of SARS-CoV-2 severity, indications for in-patient treatment, textbooks on resuscitation, outcomes, and age-associated and comorbid factors of its course, the authors examined clinical and epidemiological indicators of 22,628 patients with acute stages of moderate, severe, and extremely severe course of SARS-CoV-2, including 772 patients with long COVID, who underwent treatment in post-COVID hospital from 2020 to 2022. The study shows that during the SARS-CoV-2 pandemic, many residents of the region required hospitalization as well as admission to intensive care departments. In addition to that, elderly patients, especially those with metabolically associated pathology, form a group of patients with a high risk of a severe course of the disease, which worsens the patient’s state in accordance with the complications’ development. Thus, these patients required a special approach to the algorithm of treatment and diagnosis with an analysis of all clinical and epidemiological gerontological aspects of novel infection and the relation between the course and the outcome of the disease in patients with comorbidities.