Наследуемость соотношения длин пальцев 2D: 4D

Abstract

A Chuvashian population-based sample included 802 males and 738 females (mean age 46.98±17.10 and 48.65±16.62 years, correspondingly). Age, basic demographics, anthropometric data, reproductive indices, and x-rays of both hands were collected. Results and discussion. Familial correlations of FLR traits showed no significant correlation for spouses, however, parent-offspring (0.15-0.28, p<0.001) and sibling correlations (0.13-0.38, p<0.009) were found significant. Heritability (H2) of visual classification of FLR was 0.36 for the left and 0.28 for the right hand; finger ratio was 0.55 and 0.66, respectively; the ray ratio was 0.49 and 0.59, respectively, thus indicating the existence of a clear familial aggregation of FLR variation in the Chuvashian pedigrees, which cannot be explained by pure common environmental effects. Conclusion. Results of our study suggest the familial aggregations of finger ratio variation (for all traits) in Chuvashian pedigrees. Further research should focus on the biological mechanisms of the relationship between FLR and aging.