Abstract
Sphenoid sinus is placed deeper than the other paranasal sinuses. Sphenoid sinus is close proximity with critical structures like carotid artery, optic nerve. Because of this anatomical association, mucocele or sinusitis of sphenoid sinus has caused visual disturbance by optic neuritis. Optic neuritis is generally defined as an inflammatory neuropathy of the optic nerve usually associated with infectious, inflammatory, compressive, neoplastic, or vascular processes. Degeneration or demyelination of the optic nerve occurs and leads to vision loss. We present two cases of optic neuritis secondary to fungal sphenoid sinusitis and mucocele. All of cases are treated surgically using the endoscopic sinus surgery and intravenous antibiotics and corticosteroids. (J Clinical Otolaryngol 2011;22:111–115)
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