해양콜라겐의 생리활성기능과 화장품 소재로서의 응용

Abstract

Collagen, the most abundant and ubiquitous fibrous protein in animals, is the main architectural element of the extracellular matrix (ECM) and constitutes a large portion of connective tissue proper, skin, tendon, cartilage and bone. Collagen provides skin with tensile strength, attachment sites for skin cells, elasticity and hydration, helping maintain mechanical stability or regeneration of skin. The importance of collagen is increasingly recognized as a key source of biomaterials for cosmetics. Commercial collagen has been traditionally extracted mainly from terrestrial mammals such as cattle and pigs. However, recently, marine collagen has attracted much attention, as a mammalian collagen substitute, from biomedical researchers to the cosmetic, food, nutraceutical, pharmaceutical and biomedical industries, especially because of its easy extractability, water-solubility, safety, better chemical and physical durability, and wide availability. Thus, marine collagen is now become a valuable and widely used component in cosmetic formulation due to its significant beneficial effects on human skin. Collagens are usually extracted by acid and pepsin. Its popularity in cosmetology and dermatology is primarily associated with proven ability to enhance skin hydration and elasticity, and exhibit anti-skin aging activity. Moreover, marine collagen also has the potent antioxidant properties, thereby protecting skin cells against oxidative stress caused by free radicals and ultraviolet radiation on the skin. This study reviews literature on the skin care properties of marine collagen and its sources, extraction methods, types, structural modification, and fabrication methods for cosmetic applications.