Abstract
Migratory thrombophlebitis is a rare paraneoplastic syndrome occurred in malignancies. The association between migratory thrombophlebitis and malignancy is known as Trousseau syndrome. Thrombotic complications preceding malignancy manifestation are referred to as thrombotic mask. This paper describes successful surgical outcome of ovarian cancer associated with Trousseau syndrome. The first manifestations of this syndrome were acute proximal thrombosis in the left popliteal and left femoral vein, spontaneous arterial thrombosis, and numerous intracranial thromboses that have resulted in myocardial infarction and ischemic stroke. Later, the woman was diagnosed with ovarian cancer (T1aN0M0). All paraneoplastic signs have disappeared after a surgery for ovarian cancer. Congenital thrombophilia was an additional risk factor for thrombosis. The woman was provided with surgical, anesthetic, and intensive medical care which have improved the quality of life, increased life expectancy, and returned workability.Keywords: ovarian cancer, paraneoplastic syndrome, Trousseau syndrome, thrombotic complications, hemostasis disorders.For citation: Kalinkina E.F., Sluvko N.P., Kondrat’eva O.V., Tarasov D.G. Trousseau syndrome and ovarian cancer. Russian Journal of Woman and Child Health. 2020;3(2):95–99. DOI: 10.32364/2618-8430-2020-3-2-95-99
Highlights
Ассоциация опухолевых заболеваний и тромбоэмболических нарушений была впервые обнаружена A
This paper describes successful surgical outcome of ovarian cancer associated with Trousseau syndrome
1. Ikushima S., Ono R., Fukuda K. et al Trousseau’s syndrome: cancer-associated thrombosis
Summary
Ассоциация опухолевых заболеваний и тромбоэмболических нарушений была впервые обнаружена A. Связанный с наличием злокачественной опухоли тромбоз является второй по значимости причиной смерти онкологических больных после собственно рака. Риск венозной тромбоэмболии у больных раком в 4–7 раз выше, чем у пациентов без данной патологии. 48 лет, поступила 29.01.2018 с жалобами на дискомфорт в груди без четкой связи с физической нагрузкой, кратковременную потерю чувствительности в левой руке, кратковременное отсутствие речи, общую слабость.
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