Abstract

We report a case of tumor arising on the temporal scalp of a 50-year-old woman. The histopathological findings for the tumor revealed it to be ductal sweat gland carcinoma connected to a syringocystadenoma papilliferum (SCAP) arising on a nevus sebaceus. Mucinous stroma, considered to be deposition of hyaluronic acid, was also observed in the ductal carcinoma portion. The immunohistochemical and ultrastructural findings in the ductal carcinoma portion were compared with those in the SCAP portion. Both the ductal sweat gland carcinoma and SCAP portion showed findings compatible with the ductal portion of an sweat gland. The findings in this case suggest that the possibility that malignant tumors with sweat gland differentiation can co-exist with nevus sebaceous should be taken into consideration.

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