Abstract
Contact dermatitis (CD) is one of the most common inflammatory skin diseases caused by exposure to exogenous substances. There are 2 subtypes of CD: irritant and allergic. The first is based on an inflammatory reaction to direct chemical damage to the skin barrier; allergic CD is based on a delayed type IV hypersensitivity reaction that occurs after sensitization to a specific hapten. The most common allergens are nickel, cobalt, balsam of Peru, preservatives and dyes. Topical glucocorticosteroids are considered the gold standard in the treatment of contact dermatitis. Among all topical glucocorticosteroids, methylprednisolone aceponate 0.1% has a safe therapeutic index and is even used in children from 4 months.
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