赤毛球Ｍ・Ａ・Ｐ「日赤」を使用した自己血輸血の検討

Abstract

Since April 1991 we have carried out preoperative autologous blood storage using the RC-MAP system (Japanese Red Cross) for elective surgery. Ninety patients with an average age of 59 years and average body weight of 57kg were given Erythropoietin (6, 000 units/day) with oral iron supplements. Four-hundred ml of blood at 4-7 day intervals up to 2, 000ml were drawn 2-3 weeks prior to surgery. The surgical procedures were composed of 78 cardiac disease cases and 12 cancer cases.The blood drawn was separated into red cells stored at 4°C in MAP solution (RC-MAP), and plasma stored as FFP (fresh frozen plasma). During cardiac surgery platelet rich plasma (PRP) was also obtained by means of Hemonetics Ultralite Plasma Collection System at an early stage of surgery. Most of these autologous RC-MAP, FFP and PRP were transfused during surgery, and in a few cases the RC-MAP were also transfused during the post operative period. Average bleeding volume during surgery was 5.97±0.84ml/kg, and various laboratory data collected during hospital stay, excepting the 3 days after surgery, showed values in the normal range. In 71 cases transfusion was satisfied entirely with autologous blood components without hazards; in 19 cases some additional homologous blood was required because of surgical error or other reasons.It is concluded that our predeposit program using the RC-MAP system is both practical and economical when compared with the frozen red cell system.