Abstract

Quantification method of DNA adducts at the practical sensitivity was eagerly awaited in several study area such as mutagenesis, carcinogenesis, aging, DNA repair and molecular epidemiology. Recent development of liquid chromatography electrospray tandem mass spectrometry (LC/ESI/MS/MS) enables us to detect 25 fg of adducted deoxynucleoside, which is corresponding to a few DNA adducts in 109 bases. This means that LC/ESI/MS/MS analysis of DNA adducts reaches to the practical sensitivity.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.