Азитроміцин у клініці інфекційних хвороб

Abstract

Infectious diseases are extremely common among children, characterized by a severe course and are the leading cause of death among young children. Purpose - to increase the awareness of medical workers regarding the current trends in the therapy of infectious diseases and highlight the feasibility of using azithromycin, based on the latest international recommendations. This review presents the main characteristics of the most common infectious diseases, as well as modern approaches to their treatment. Antibiotic therapy is an integral part of the treatment of most infections. Azithromycin is an antibacterial drug from the group of macrolides, characterized by a wide range of applications in pediatric practice. We considered the mechanisms of its bacteriostatic, antimicrobial, immunomodulatory activity and presented the results of numerous studies on the effectiveness of azithromycin use in infectious diseases. Conclusions. Azithromycin is an effective and proven antibacterial agent for various pathological conditions, such as diseases of the lower respiratory tract (pneumonia, acute bronchitis, bronchiolitis), acute intestinal infections and Lyme borreliosis. Studies of this drug show good tolerability, low rate of adverse reactions and high safety profile, which allows it to be prescribed to young children, and bacteriostatic, antimicrobial, immunomodulatory and bactericidal activity contribute to a wide range of applications in pediatric practice. No conflict of interests was declared by the authors.