Abstract
Extranodal marginal zone B-cell lymphoma, which is a low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type, can occur in the gastrointestinal tract, salivary gland, thyroid, orbit, lung, breast and skin.We report two cases of primary cutaneous marginal zone B-cell lymphoma. The first case was a 53-year-old man who presented with multiple cutaneous nodules on his back. The second case was a 35-year-old female who presented with a solitary cutaneous nodule on her left forearm. Histologically, both tumors were characterized by reactive lymphoid follicles and proliferation of centrocyte-like cells and plasma cells. Centrocyte-like cells were shown a CD20+, but CD5- and CD10-immunophenotype. Furthermore, a monoclonal pattern of immunoglobulin light chain in plasma cells was found in both cases. Monoclonal rearrangement of the JH gene was detected via PCR. [Skin Cancer (Japan) 2002; 17: 288-292]
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
