ВИДИ БІОПРИНТЕРІВ ДЛЯ ДРУКУ ОРГАНІВ

Abstract

3D bioprinting is a new revolutionary field of regenerative medicine. Bioprinting can be defined as a layer-by-layer formation of an object made of different biomaterials (living cells) based on a pre-created computer model. To date, the development of three-dimensional structures loaded with cells for imitation of body tissue plays an important role not only in tissue engineering but also in drug delivery research and cancer research. The lack of donors is a serious medical problem, with the trend of donors becoming smaller and the number of patients in need of donor organs increasing. As bioprinting has great potential to address such global issues as transplantation, animal experiments, the use of experimental drugs for surveillance, it is important to consider this topic.In this brief overview, different methods of manufacturing biological structures are identified and compared: laser bioprinting, inkjet-based bioprinting, and extrusion-based bioprinting. The advantages and problems of each technique are determined, as well as the principle of operation of each technique for different states of bio-ink.These three methods have been found to have different effects on cell viability, resolution and print accuracy. In addition, the choice of materials and their concentration was also influenced by the choice of bioprinters. Each technique demonstrated individual advantages and disadvantages