Abstract
EIA and PA test are simple, rapid and reliable methods for detection of anti-ATLA antibodies and suitable for mass screening of sera from blood donors. These methods, however, have some non-specific reactions in the procedures and sometimes show discrepancies in the detection rate. In this report comparative study using these methods and Weatern blotting method are performed.ETA and PA test showed coincidence in the detection of sera with relatively high titer antibodies, whereas discrepancy was observed in the screening of sera with low titer reactions. Only PA test gave positive reactions in the early phase of seroconversion after transfusions. Non-specific reactions were recognized in the sera with antinuclear antibodies and in the sera of patients with malignant tumor. In ETA, inhibition tests are required on the sera among cut off index (usually 0.10OD) and 0.30OD. In PA test, re-examinations using Western blotting method or other method are required in the sera with antibody titer among 1:16 and 1:64.
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