현대 생체시계 연구를 바탕으로 재조명한 <황제내경 소문 사기조신대론>의 계절에 따른 생활양식

Abstract

Objectives In <Hwangjenaegyeong Somun Sagijosindaelon>, the climate change according to the four seasons is explained, and how to manage health by adjusting the lifestyle is recorded. Since the concepts of yin-yang and the four seasons are being re-examined in modern times with the discovery of biological clock genes, we attempted to scientifically reinterpret the classic text. Methods We reinterpreted the classic text and used keywords such as “circadian clock,” “circadian gene,” “seasonal variation,” “metabolism,” “environment,” and “climate” to search PubMed and Google Scholar for relevant articles. References in relevant articles were also considered. Results In mammals, the suprachiasmatic nucleus and the autonomic nervous system regulate seasonal variation in physiological responses in response to changes in the length of the external light cycle. Since most people now live in indoor environments with air conditioning and lighting, seasonal circadian rhythms have decreased in comparison to 100 years ago. Disrupting the circadian rhythm is equivalent to attacking the body from within by disrupting the order in the body. To restore and fine-tune the circadian rhythm and prevent serious diseases before the body's dysfunction becomes chronic, healthy eating, proper sleep, and adequate physical activity are required. Conclusions With the recent focus on global warming and environmental pollution, interest in climate change-related health issues is growing. Global cooperation will be required, and the effects of climate change on ecosystems and environments, as well as their impact on people's health, must be continuously monitored to protect the global environment and public health.